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Alpha
Lipoic Acid May Alleviate DSPN
A collaborative study between Mayo Clinic and a medical center in
Russia found that alpha lipoic acid (ALA) rapidly reduces the frequency
and severity of symptoms of the most common kind of diabetic neuropathy,
diabetic sensorimotor polyneuropathy (DSPN) - without the side effects
associated with medications commonly used to treat the condition.
The study included 120 type 1 or 2 diabetic patients, ages 18 to
74, who were given intravenous ALA or placebo in 14 doses over three
weeks.
"There appears to be a rather large effect on the pain of diabetic
neuropathy with ALA," says study author Peter Dyck, MD. "The
magnitude of the change is considerable. We also found some improvement
in neurologic signs and nerve conduction. We were surprised by the
magnitude and the rapidity of the response."
Diabetes Care - March 2003;26:770-6. http://care.diabetesjournals.org/
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